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Updated: Jul 16, 2026

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
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Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

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多Omics洞察到三角膜发育不良的分子机制:在老鼠蛋白质和代谢学研究

Zhenhui Huo1,2,3, Huijun Kang1, Peishuo Liu4

  • 1Department of Orthopaedic Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.

PloS one
|August 11, 2025
PubMed
概括

这项研究揭示了小鼠模型中使用蛋白质组学和代谢组学在三角膜发育不良 (TD) 中的分子变化. 关键发现包括改变的肌酸,L-酸和特定的代谢途径,为TD机制提供了洞察力.

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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

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相关概念视频

Lethal Alleles02:41

Lethal Alleles

Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...