通过两代人的家族传输神经表现的精神算术两代人的神经表现
Charlotte Constant-Varlet1, Tomoya Nakai2,3, Léa Longo1
1Centre de Recherche en Neurosciences de Lyon, INSERM U1028 - CNRS UMR5292, Université de Lyon 1, Bron 69500, France.
概括
父母和孩子在算术处理中的大脑相似性,特别是在insula和前中心环,预测了共享的数学和工作记忆技能. 这种神经相似性对于面临更大的挑战的家庭尤为重要.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 发展心理学 发展心理学
背景情况:
- 父母的技能对孩子的认知发展有很大影响.
- 了解代际认知技能传播的神经机制至关重要.
- 亲子大脑相似性和认知技能相似性之间的关系尚不清楚.
研究的目的:
- 研究从母亲传给儿童的认知功能传播的神经标记.
- 为了检查大脑相似性是否预测家族双层中的认知技能相似性.
- 确定支持算术技能的代际传播的大脑区域.
主要方法:
- 使用功能性磁共振成像 (fMRI) 测量37个母婴二合体的心理算术期间的大脑活动.
- 采用多变量搜索灯表示相似性分析来比较成人和儿童之间的神经表示.
- 检查了特定大脑区域的特定家族神经传输及其与母亲技能水平的相互作用.
主要成果:
- 在广泛的大脑网络中,无论家庭关系如何,在算术处理 (问题大小效应) 中发现了显著的成年儿童神经相似性.
- 特定于家族的神经传输在双边前侧胰岛和左前中心环中被确定.
- 这些区域的母婴神经相似性预测了数学和工作记忆的行为相似性,特别是在具有较低技能母亲的双中.
结论:
- 与任务相关的代际神经成像可以揭示参与认知技能传播的大脑区域.
- 增加亲子神经相似性可能是共享认知能力的关键预测因素,特别是在具有父母困难的二中.
- 研究结果表明,学习障碍的潜在神经标志物可以通过家族传播模式来识别.
更多相关视频
12:28Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
Published on: June 3, 2020
17.5K
08:22A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
Published on: December 1, 2017
8.7K
相关概念视频
Pedigree Analysis
85.2K
Overview
85.2K
Law of Segregation
67.1K
When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.
67.1K
Probability Laws
41.7K
Overview
41.7K
Genomic Imprinting and Inheritance
35.3K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
35.3K
Non-nuclear Inheritance
21.7K
Most DNA resides in the nucleus of a cell. However, some organelles in the cell cytoplasm—such as chloroplasts and mitochondria—also have their own DNA. These organelles replicate their DNA independently of the nuclear DNA of the cell in which they reside. Non-nuclear inheritance describes the inheritance of genes from structures other than the nucleus.
21.7K
Animal Mitochondrial Genetics
8.0K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
8.0K
