刺激性肠综合征 刺激性肠综合征
Katarina B Greer1, Shahnaz Sultan2
1Case Western Reserve University and Cleveland Veterans Affairs Medical Center, Cleveland, Ohio (K.B.G.).
Annals of internal medicine
|August 11, 2025
概括
刺激性肠综合征 (IBS) 是一种常见的肠道疾病. 这篇文章回顾了IBS的新诊断和治疗策略,包括药物和生活方式的改变.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
背景情况:
- 刺激性肠综合征 (IBS) 是一种普遍存在的胃肠道疾病,影响4%-10%的人口.
- 这是一种慢性疾病,其特征是腹部疼痛,肠道习惯改变,膨胀或膨胀.
- IBS的亚型包括便秘的IBS (IBS-C),腹的IBS (IBS-D) 和混合的IBS (IBS-M).
研究的目的:
- 要总结最近在IBS的诊断和管理方面的进展.
- 讨论当前和新兴的药理和非药理治疗选择.
- 强调基于IBS亚型和症状严重程度的个性化治疗计划的重要性.
主要方法:
- 关于IBS诊断和治疗的最新文献的综述.
- 讨论基于症状的诊断标准.
- 探索各种治疗方式,包括饮食,生活方式,药理和非药理干预.
主要成果:
- IBS的诊断越来越多地基于症状标准,允许更早的识别.
- 治疗策略越来越个性化,针对特定的IBS亚型和烦人的症状.
- 新的药理和非药理选择为IBS患者提供了更好的管理.
结论:
- 诊断标准的进步有助于及时诊断IBS.
- 个性化治疗方法,包括新疗法,对于有效的IBS管理至关重要.
- 改变生活方式和向治疗的结合改善了IBS患者的治疗结果.
相关概念视频
Irritable Bowel Syndrome I: Introduction
382
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
382
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
245
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
245
Irritable Bowel Syndrome III: Medical and Nursing Management
302
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
302
Chronic Bowel Disorders: Introduction
541
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
541
Drugs for Treatment of Diarrhea-Predominant IBS
294
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
294
Inflammatory Bowel Disease I: Ulcerative Colitis
324
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
324


