巴西脑儿童的阻塞性睡眠呼吸暂停综合征:一项多中心研究
Bruno Leonardo Scofano Dias1, Fernanda Marinho de Lima1, Daniela Fava1
1Rede SARAH de Hospitais de Reabilitação, Brazil.
Jornal de pediatria
|August 11, 2025
概括
阻塞性睡眠呼吸暂停综合征 (HR-OSAS) 的高风险在患有脑 (CP) 的巴西儿童中更为常见,特别是那些严重运动障碍 (GMFCS V) 的儿童. 巴拉丁桃体缩是一个关键的相关因素.
科学领域:
- 儿科神经学 儿科神经学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 阻塞性睡眠呼吸暂停综合征 (OSAS) 是儿童的一个重大问题.
- 由于各种因素,脑 (CP) 可能会增加OSAS的风险.
- 查工具对于识别高风险儿童至关重要.
研究的目的:
- 确定巴西儿童中阻塞性睡眠呼吸暂停综合征 (HR-OSAS) 高风险的患病率.
- 分析HR-OSAS与人口,临床和功能变量的关联,包括总运动功能分类系统 (GMFCS).
- 评估儿科阻塞性睡眠呼吸暂停查工具 (PosaST) 的实用性.
主要方法:
- 进行了一项多中心,横截面,探索性研究.
- 包括312名患有脑膜炎的巴西儿童.
- 儿科阻塞性睡眠呼吸暂停查工具 (PosaST) 用于HR-OSAS查.
主要成果:
- 在患有CP的儿童中,HR-OSAS的患病率为9.0% (GMFCS I-V).
- 与GMFCS I-IV (6.4%) 相比,GMFCS V (14.7%) 的HR-OSAS患病率显著更高.
- 巴拉丁桃体缩与HR-OSAS显著相关,特别是在GMFCS V.中.
结论:
- 与典型发育的儿童相比,HR-OSAS在巴西儿童中更为普遍,特别是在GMFCS V中.
- 桃体缩是这个人群中HR-OSAS的重要危险因素.
- PosaST可能是一个有用的查工具HR-OSAS在巴西儿童CP,但需要进一步的研究来建立切断分数.
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