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皮层发育中的时空模式:年龄,青春期和9至13岁的个体变化
Katherine L Bottenhorn1,2, Jordan D Corbett1, Hedyeh Ahmadi1
1Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA 90089.
概括
青少年大脑的发育遵循传感运动与关联 (S-A) 轴,但个体变化有很大差异. 皮层发育的这种变化受到年龄,性别和青春期的影响.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 人类的神经成像
背景情况:
- 皮层发育的时间和节奏在神经解剖学上沿着传感运动与关联 (S-A) 轴变化.
- 关于SA轴的先前研究经常使用具有广泛年龄范围的横截面数据.
研究的目的:
- 调查青春期早期沿S-A轴的皮质组织的发育变化和个体变异性.
- 评估年龄,性别和青春期如何影响S-A对齐的个体差异.
主要方法:
- 利用来自青少年大脑认知发育研究 (ABCD Study®) 的一个大型纵向样本 (N = 2487-3747).
- 通过皮质厚度,微观架构和静止状态低频振荡来评估神经发育.
- 分析了与年龄相关的变化和大脑发育中的个体SA对齐.
主要成果:
- 沿SA轴识别了与年龄相关的线性和二次性大脑变化.
- 在SA对齐中观察到相当大的个体变异性,掩盖了群体层面的模式.
- 在个体内的不同神经发育方面的SA模式之间发现了有限的对应性.
- 通过年龄,性别和青春期发育解释了一些个体差异.
结论:
- 大脑发育的年龄差异在S-A轴上沿着S-A轴进展.
- 在青少年大脑发育模式中存在显著的个体差异.
- 性和青春期部分解释了个体发展轨迹的差异.
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