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遵守地中海饮食对认知表现和癌症生存率之间的关系的影响
Andrew McLeod1, Kelsey Gabel2, Kaitlin Chakos2
1Institute for Health Research and Policy, University of Illinois Chicago (UIC), Chicago, IL, USA. amcleo2@uic.edu.
Journal of cancer survivorship : research and practice
|August 11, 2025
概括
坚持地中海饮食的癌症幸存者与认知功能有较强的负面关联,特别是在侵入方面. 需要进一步的研究来确认癌症幸存者的这些发现.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 认知神经科学 认知神经科学
背景情况:
- 癌症及其治疗常常导致幸存者的认知障碍.
- 尚未确定这种认知衰退的可修改风险因素.
- 地中海饮食可能会提供对认知障碍的保护性益处.
研究的目的:
- 研究认知表现与癌症存活率之间的关系.
- 为了确定遵守地中海饮食是否会改变癌症史和认知功能之间的关联.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) 的数据.
- 使用aMed分数 (0-9) 评估地中海饮食的坚持.
- 使用线性回归模型评估认知功能,包括处理速度,注意力,记忆和执行功能.
主要成果:
- 癌症史与整体认知表现没有显著的关联 (p > 0.05).
- 观察到地中海饮食的坚持和癌症史之间的显著相互作用 (p = 0.03).
- 坚持高地中海饮食与癌症史和侵入次数 (认知控制的衡量标准) 之间更大的负面关联有关.
结论:
- 癌症病史表明,与那些坚持地中海饮食较低的人相比,那些坚持地中海饮食较高的人对认知的影响更为不利.
- 横截面设计,癌症幸存者的有限样本以及缺乏治疗数据需要进一步调查.
- 需要包括治疗细节的前性研究来验证这些初步发现,并为癌症幸存者提供饮食建议.
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