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Updated: Sep 11, 2025

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在线粒体疾病中重写核表观遗传脚本,作为控制异质体的战略

María J Pérez1,2, Rocío B Colombo1, Sebastián M Real1,3

  • 1Instituto de Histología y Embriología de Mendoza (IHEM), Universidad Nacional de Cuyo, CONICET, Mendoza, Argentina.

EMBO molecular medicine
|August 11, 2025
PubMed
概括

向核DNA甲基化可以减少有害的线粒体DNA突变. 这种表观遗传方法有选择性地损害具有高突变负载的细胞,为线粒体疾病提供了新的治疗策略.

关键词:
基因甲基化 DNA 甲基化表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.不同质体性质素的形成线粒体DNA是线粒体的DNA.线粒体疾病 线粒体疾病

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