植物抑制ROS1的表达,以减弱热引起的转子子子爆发
Lingjiao Fan1,2, Yuqing Jing3, Xinyu Liu3
1State Key Laboratory of Wheat Improvement, School of Advanced Agricultural Sciences, Peking University, Beijing, China.
Nature plants
|August 12, 2025
概括
热应激通过减少DNA甲基化,防止可移植元素的激活和保护植物基因组的稳定性来抑制抑制沉默1 (ROS1) 表达.
科学领域:
- 植物分子生物学 植物分子生物学
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
- 基因组学就是基因组学.
背景情况:
- 沉默抑制剂1 (ROS1) 是一种控制植物DNA甲基化模式的DNA脱甲基酶.
- ROS1的表达是由其促进体中的DNA甲基化调节的,但其压力诱导的调节尚不清楚.
研究的目的:
- 研究热应激下ROS1调节的机制和生物学意义.
- 了解热应激如何影响ROS1表达及其对基因组稳定性的下游影响.
主要方法:
- 在热应激下对ROS1促进体的DNA甲基化分析.
- 染色体免疫沉以研究SUVH1和SUVH3结合.
- 产生和分析具有改变ROS1表达的转基因植物.
主要成果:
- 热应激降低了ROS1促进体DNA甲基化,抑制了ROS1的表达.
- 在热应激下,SUVH1和SUVH3与ROS1促进体的解离允许染色质循环和转录抑制.
- 在热应激下外源ROS1表达导致可转移元素低甲基化和ONSEN逆转移子激活.
结论:
- 热诱导的ROS1转录抑制作为一个车,在热应激期间限制可转换元素的激活.
- 这种调节机制在植物物种中得到保护,对于在压力条件下保持基因组稳定性至关重要.
相关概念视频
Overview of Transposition and Recombination
16.1K
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
16.1K
Transgenic Plants
7.4K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
7.4K
Cell Signaling in Plants
5.7K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
5.7K
Responses to Heat and Cold Stress
13.8K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
13.8K


