韩国糖尿病黄斑的治疗趋势 (TRACK) 研究:一个前性的多中心研究
Min Seok Kim1, Kwangsic Joo1, Yong-Un Shin2
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Korean journal of ophthalmology : KJO
|August 12, 2025
概括
与临床试验相比,在韩国的真实世界糖尿病黄斑 (DME) 治疗显示,与临床试验相比,抗VEGF注射和访问减少. 这种较低的治疗频率可能会导致DME患者的视觉结果低于最佳.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 医学经济学 医学经济学
背景情况:
- 糖尿病黄斑 (DME) 是糖尿病患者视力丧失的主要原因.
- 了解现实世界的治疗模式对于优化患者的治疗结果至关重要.
- 之前的研究往往侧重于临床试验数据,这些数据可能不反映日常实践.
研究的目的:
- 评估韩国DME.患者的现实世界功能和解剖结果.
- 分析韩国DME的治疗模式和眼科检查趋势.
- 为了比较中心参与 (CI DME) 和非中心参与 (非CI DME) 组之间的结果.
主要方法:
- 一项前性多中心观察性研究,涉及2017-2022年期间209名患有DME的成年人.
- 根据OCT发现,患者被分为CI DME和非CI DME.
- 在24个月内分析了BCVA,CST和治疗/检查模式的连续变化.
主要成果:
- 在CI DME组中,中部亚骨厚度 (CST) 显著下降 (P=0.001).
- 在两组中,最佳校正视敏度 (BCVA) 保持不变.
- 在CI DME组接受了更多的抗VEGF注射 (3.8对2.0,P=0.004) 和更频繁的访问 (15.8对11.3,P=0.017).
结论:
- 在韩国,实际的DME治疗和监测频率低于临床试验.
- 这种较低的频率可能会导致DME患者的视觉结果不足.
- 需要进一步的研究来优化DME在常规临床实践中的管理.
更多相关视频
11:13Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
Published on: April 7, 2016
9.3K
10:24Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
10.3K
相关概念视频
01:27Open Angle Glaucoma: Treatment
568
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
568
01:28Angle Closure Glaucoma: Treatment
681
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
681