营养不良与败血症相关的痴呆症之间的关联:对MIMIC-IV数据库的回顾性分析
Weixi Tan1, Rongfang Duan1, Chengcheng Zeng1
1School of Nursing School of Public Health, Yangzhou University, Yangzhou, China.
Nursing in critical care
|August 12, 2025
概括
营养不良显著增加了败血症患者 Delirium 的风险. 解决ICU中的营养状况对于改善结果和潜在降低医疗保健成本至关重要.
科学领域:
- 临界护理医学 临界护理医学
- 营养科学 营养科学
- 神经学 神经学
背景情况:
- 败血症相关妄 (SAD) 是败血症的一个常见的神经复杂症.
- 抑郁症增加死亡率,并导致长期的神经精神问题,如焦虑和认知障碍.
- 败血症患者的营养状况和SAD之间的关系尚不清楚.
研究的目的:
- 为了调查营养不良和败血症相关妄 (SAD) 在重症监护室 (ICU) 患者的发病率之间的关联.
主要方法:
- 对接受ICU治疗的成人败血症患者的回顾性分析.
- 使用后勤回归和倾向得分匹配来分析营养不良和妄想之间的关联.
- 进行了敏感性分析,包括E值,以证实发现.
主要成果:
- 这项研究包括25716名患者,其中3132名患者营养不良.
- 营养不良患者患狂妄症的风险增加了两倍 (26.56%对12.90%).
- 营养不良与妄想发生有显著的正相关性 (OR=2.07,95% CI=1.88-2.29),在所有灵敏度分析中一致.
结论:
- 营养不良是败血症患者妄的重要危险因素.
- 建议在ICU中对营养不良的败血症患者进行早期评估和营养干预.
- 解决营养不良可能会减少妄想发病率,改善患者的治疗结果,降低医疗保健成本.
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