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肝毒性的系统分析:结合文献挖掘和AI语言模型

Chris Bauer1, Long Tran Duc Dang1, Twan van den Beucken2

  • 1MicroDiscovery GmbH, Berlin, Germany.

Frontiers in artificial intelligence
|August 12, 2025
PubMed
概括

自动化文本挖掘有效地从超过5万种化合物中识别出潜在的肝毒性物质. 大型语言模型在预测肝损伤方面表现出卓越的表现,优于传统的文本挖掘方法.

关键词:
人工智能 (AI) 是一种人工智能.肝毒性 肝毒性 肝毒性大型语言模型 (LLM)文本采矿 文本采矿是什么毒理学 毒理学 毒理学

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Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
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