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Updated: Sep 11, 2025

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype
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利用白血病干细胞中对PI3激酶抑制的表观遗传抵抗机制

Shira G Glushakow-Smith1,2,3,4, Imit Kaur1,4, Simone Sidoli5

  • 1Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY.

bioRxiv : the preprint server for biology
|August 12, 2025
PubMed
概括

在急性髓性白血病 (AML) 中准白血病干细胞 (LSC) 是具有挑战性的. 一种针对PI3K和EZH1/2的新型组合疗法克服了耐药性,为AML患者提供了一个有前途的治疗策略.

关键词:
在 EZH2 中使用.在PI3K中,PI3K是指PI3K.在 PRC2 中,PRC2 是 PRC2 的第一个类型.急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.

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