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Updated: Jun 15, 2026

Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors
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Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

Published on: January 19, 2015

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通过MAS NMR确定PF-46396抑制HIV-1成熟的结构基础

Roman Zadorozhnyi, Caitlin M Quinn, Kaneil K Zadrozny

    bioRxiv : the preprint server for biology
    |August 12, 2025
    PubMed
    概括

    这项研究揭示了HIV-1成熟抑制剂PF-46396与囊蛋白组合结合的原子结构. 这些发现解释了PF-46396是如何工作的,并提供了对潜在药物耐药性机制的见解.

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    Identification of Nucleolar Factors During HIV-1 Replication Through Rev Immunoprecipitation and Mass Spectrometry09:38

    Identification of Nucleolar Factors During HIV-1 Replication Through Rev Immunoprecipitation and Mass Spectrometry

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