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Updated: Sep 11, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
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DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

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可编程的转化抑制通过分子-寡核酸合物

Siyi Wang, Joanna R Kovalski, Francisco J Zapatero-Belinchón

    bioRxiv : the preprint server for biology
    |August 12, 2025
    PubMed
    概括

    研究人员开发了RocASO,一种新型的结合物,将Rocaglamide A (RocA) 与反意义寡核酸 (ASO) 联系起来. 这项技术使得有针对性的mRNA翻译抑制能够提高功效和特异性,显示出治疗潜力.

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