人类皮层在感觉-关联轴上组织动态的共同波动
De-Zhi Jin1, Changsong Zhou2, Xi-Nian Zuo3,4,5
1School of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.
bioRxiv : the preprint server for biology
|August 12, 2025
概括
大脑的功能网络基于振幅的过渡,在高振幅期间有感觉运动系统活跃,在低振幅期间有关联/边缘系统活跃. 这种组织通过发展和外部刺激来完善.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 系统神经科学 系统神经科学
背景情况:
- 人类大脑的功能组织依赖于协调的神经波动.
- 了解这些大规模的协同波动在不同的振幅水平上如何过渡至关重要,但仍然在很大程度上是未知的.
研究的目的:
- 调查功能大脑网络相互作用的幅度依赖过渡的规则.
- 为量化这些动态重组,引入一种新型指标 - - 同波动得分.
主要方法:
- 使用了静止状态功能磁共振成像 (fMRI) 数据.
- 引入并应用"共波动得分"来分析与全球振幅动态相对的瞬间功能相互作用.
- 检查了多个独立样本的数据,包括高分辨率的7T fMRI.
主要成果:
- 识别了与传感运动关联 (SA) 轴对齐的截然不同的振幅依赖的共波动状态.
- 感觉运动网络主导高振幅状态,关联系统在中间振幅中壮成长,边缘系统参与低振幅状态.
- 观察到这个层次结构从童年到成年期的发展精细化和在外部刺激下适应性重新配置.
结论:
- 感觉运动关联 (SA) 轴作为振幅依赖大脑网络转换的基本组织原则.
- 大脑通过幅度分层的交互来动态平衡外部处理 (高幅度) 与内部认知/情绪 (中低幅度).
- 这个框架将暂时协调与稳定的功能架构集成在一起,提供了对整个发育过程中的大脑动态和对刺激的反应的见解.
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