印度尼西亚农村地区接种疫苗,疫苗类型和长期COVID之间的关联
Sujarwoto Sujarwoto1, Holipah Holipah1, Sri Andarini1
1Department of Public Administration, University of Brawijaya, Malang, Indonesia.
Frontiers in public health
|August 12, 2025
概括
mRNA COVID-19 疫苗显著降低了长期COVID的风险,特别是在完整的疫苗接种计划下. 这对于农村,服务不足的人口来说至关重要,以减轻长期健康影响.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 疫苗学 疫苗学 疫苗学
背景情况:
- 长期COVID是SARS-CoV-2后的重大健康问题,特别是在资源有限的农村环境中.
- 在不同人群中,针对长期COVID的COVID-19疫苗的有效性仍然不清楚.
研究的目的:
- 为了调查疫苗接种状态,疫苗类型和印度尼西亚马兰县长期COVID之间的关联.
- 评估mRNA与非mRNA疫苗对长期COVID风险的影响.
主要方法:
- 对5,735名患有COVID-19的成年人的横截面分析 (2022年6月至2023年6月).
- 长期COVID被定义为感染后持续≥12周的症状.
- 多变量后勤回归用于分析疫苗接种状态,疫苗类型和长期COVID,根据疫苗平台和剂量进行分层分析.
主要成果:
- 56.2%的参与者报告了长期的COVID.
- 与未接种疫苗的个人相比,mRNA疫苗 (Moderna,Pfizer) 与长期COVID的几率显著降低.
- 非mRNA疫苗 (Sinovac) 与增加的几率有关;mRNA疫苗观察到剂量反应关系.
结论:
- 在印度尼西亚农村地区,mRNA COVID-19 疫苗和完整的疫苗接种计划提供了对长期COVID的强有力的保护.
- 改善mRNA疫苗和助推剂的获取对于减少贫困人口的长期COVID-19后果至关重要.
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