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Updated: Sep 11, 2025

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
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Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag

Published on: December 14, 2017

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在LARGE-PD上进行的基因型-表型关联研究揭示了与帕金森病相关的新型位置

Thiago P Leal1, Emily Waldo1, Felipe Duarte-Zambrano1,2

  • 1Genomic Medicine Institute, Cleveland Clinic Research, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, United States of America.

medRxiv : the preprint server for health sciences
|August 12, 2025
PubMed
概括

这项研究在拉丁美洲人群中确定了新的帕金森病 (PD) 遗传风险位,包括ITPKB的显著变异. 这些发现凸显了在基因研究中多样化的种群对于推进PD精准医学的重要性.

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Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease08:09

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Genome-wide Association Studies-GWAS01:11

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