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Updated: Sep 11, 2025

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
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纳姆普特哈普洛缺陷是一种附带致命的治疗脆弱性,在高风险的骨髓瘤恶性瘤中具有TP53无活化

Madhavi D Senagolage1, Hunter Z Blaylock1,2, Saira Khan1

  • 1Department of Pathology, The University of Chicago, Chicago, IL.

Blood neoplasia
|August 12, 2025
PubMed
概括

单体7和7q删除在髓状瘤恶性瘤中造成了脆弱性. 用抑制剂向尼古丁胺胺酸转移酶 (NAMPT) 显示出治疗前景,特别是与PARP抑制剂结合使用时.

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