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酵母可以通过增强结肠屏障功能和调节结肠微生物群来缓解新生儿羔羊的腹

Dingkun Fan¹, Rui Zong^1,2, Chengrui Zhang¹

¹Key Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research of Chinese Academy of Agricultural Sciences, Beijing, China.

Frontiers in veterinary science

|August 12, 2025

概括

酵母补充剂通过改善肠道健康和调节肠道微生物群,显著降低了新生儿羔羊的腹发病率. 这种饮食策略有望改善羔羊的健康状况并减少损失.

科学领域:

动物科学动物科学
微生物学微生物学
免疫学免疫学免疫学

背景情况:

新生儿羔羊因肠道组织和微生物群不成熟而容易患腹,这导致畜牧业的经济损失很大.
从酵母菌株中提取的酵母具有抗菌性质,并正在探索它们在牲畜中的潜在健康益处.

研究的目的:

调查酵母补充剂对新生儿羔羊腹发病率的影响.
阐明潜在的机制,包括炎症反应,抗氧化能力,结肠屏障功能和微生物群变化.

主要方法:

32只一天大的羊羔被分为四组,每天服用不同剂量的酵母 (0,500,1000,2000毫克/天).
分析了便分数,腹发病率,结肠粘膜炎症因子 (IL-4,IL-10,IL-1β,IL-6),抗氧化能力,屏障功能和结肠微生物群组成.

主要成果:

酵母补充剂显著降低了分数和腹发病率 (p < 0.05).
补充剂在结肠粘膜中增加了抗炎因素 (IL-4,IL-10) 和减少了促炎因素 (IL-1β,IL-6) (p <0.05).
观察到肠道抗氧化能力的增强,结肠屏障功能的加强,以及微生物群的有利转变 (红斑菌增加,葡萄球菌和埃舍里希亚_希格拉菌减少) (p < 0.05).

结论:

酵母可以有效地改善新生儿羔羊的腹.
这些好处归因于肠道微生物群的调节和增强结肠屏障功能.
为获得最佳效果,建议每天服用2000mg酵母的剂量.

关键词:

屏障的功能是屏障的功能.这是一种炎症炎症炎症炎症.羊羔羊羔羊羔羊羔我们的微生物群.酵母是酵母中的一种.

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