酒精使用障碍,但不是当前的酒精使用与艾滋病毒感染者在护理中的下降有关
Mindy Dai1, Geetanjali Chander1, Allison R Webel1
1University of Washington, Seattle, WA, United States.
AIDS (London, England)
|August 12, 2025
概括
艾滋病毒感染者 (PWH) 的酒精使用障碍 (AUD) 与跌倒风险增加有关,但不是目前的饮酒水平. 需要进一步的研究来了解为什么AUD,而不是急性中毒,预测PWH下降.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 成 药物 药物 药物 药物
背景情况:
- 关于艾滋病毒感染者 (PWH) 饮酒和跌倒之间的联系的研究有限.
- 严重的偶发性酒精使用在PWH中很常见,这使得这种联系成为一个重大的公共卫生问题.
研究的目的:
- 调查酒精使用与PWH中的跌幅之间的关联.
- 要区分当前酒精消费与酒精使用障碍 (AUD) 对跌倒风险的影响.
主要方法:
- 在8个CNICS站点中对5,729个PWH进行横截面研究 (2021-2024年).
- 通过AUDIT-C和自我报告的AUD评估的酒精使用. 使用FROP-Com组件测量下降.使用FROP-Com组件测量下降.
- 对人口和地理因素进行调整的相对风险模型.
主要成果:
- 22%的PWH在过去一年中报告至少一次下降.
- 酒精使用障碍 (AUD) 与较高的跌倒风险 (PR=1.54) 和较高的跌倒数量有关.
- 目前的酒精使用措施,包括大量的偶尔饮酒,与跌倒没有显著的关联.
结论:
- 跌倒在PWH中很常见,并且与酒精使用障碍 (AUD) 相关,不一定是当前的酒精消费.
- 这些发现表明,AUD的潜在慢性影响,而不是急性中毒,可能导致PWH下降.
- 建议进行纵向研究,以阐明AUD与此种人群中跌倒相关的机制.
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