相关实验视频

Updated: May 2, 2026

Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques
10:52

Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques

Published on: June 1, 2016

11.6K

在细胞分辨率下使用质谱成像和MALDI-IHC使用细胞分辨率在粉样β斑中的类胺和蛋白质的空间映射

Christopher J Good1, Andrew P Bowman1, Corinna Klein2

  • 1AbbVie Inc., North Chicago, Illinois, USA.

Journal of mass spectrometry : JMS
|August 12, 2025
PubMed
概括

质谱成像显示阿尔茨海默病模型中粉样斑块周围的脂质和蛋白质变化. 这种先进的成像工作流程通过在细胞分辨率上绘制分子分布来帮助药物发现.

更多相关视频

Sublimation of DAN Matrix for the Detection and Visualization of Gangliosides in Rat Brain Tissue for MALDI Imaging Mass Spectrometry08:36

Sublimation of DAN Matrix for the Detection and Visualization of Gangliosides in Rat Brain Tissue for MALDI Imaging Mass Spectrometry

Published on: March 23, 2017

11.0K
Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry09:31

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

Published on: March 7, 2019

10.8K

相关概念视频

MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
5.8K