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Updated: Sep 11, 2025

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

Published on: December 30, 2016

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正常的Treg稳态和抑制功能需要FOXP1和FOXP4两种

Dachuan Dong1, Vishal J Sindhava2, Ananthakrishnan Ganesan3

  • 1Geriatric Research Education and Clinical Center, Veterans Administration Palo Alto Health Care System, Palo Alto, United States of America.

JCI insight
|August 12, 2025
PubMed
概括

FOXP1和FOXP4蛋白对调节性T细胞 (Treg) 功能至关重要. 它们在Tregs中的联合缺席导致免疫功能障碍,自身免疫和小鼠的早期死亡.

关键词:
适应性免疫是一种适应性免疫.这是一种自身免疫力.免疫学 免疫学 免疫学这是Tregs.

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