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Updated: Sep 11, 2025

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
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Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

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在TLR7和TLR9中分离的TIR信号域控制对系统性自身免疫的相反影响

Claire Leibler1, Kayla B Thomas1, Coralie Josensi2

  • 1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, United States of America.

The Journal of clinical investigation
|August 12, 2025
PubMed
概括

具有悖论意义的是,通类受体 (TLR) 7和9的信号传递对狼有不同的影响. 这项研究揭示了TLR7和TLR9的Toll-Interleukin 1受体 (TIR) 域决定了疾病的结果,解决了长期存在的TLR自免疫性悖论.

关键词:
这是一种自身免疫力.免疫学 免疫学 免疫学这是天生的免疫力.狼是一种狼.

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