在ELSA-巴西队列中心力衰竭的发病率和危险因素
Ana Paula de Oliveira Lédo1, Sheila Maria Alvim Matos2, Maria da Conceição Chagas de Almeida3
1Graduate Program in Medicine and Health (PPgMS), Faculty of Medicine, Federal University of Bahia (UFBA), Salvador, Bahia, Brazil.
PloS one
|August 12, 2025
概括
在巴西,随着时间的推移,心力衰竭的发生率有所增加,老年和肥胖是关键的危险因素. 早期检测和公共卫生策略对于管理这种情况至关重要.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 由于发病率和死亡率高,心力衰竭 (HF) 构成了全球重大健康挑战.
- 纵向研究对于了解不同人群中HF发病率和风险因素至关重要.
研究的目的:
- 为了确定心力衰竭 (HF) 的发生率随着时间的推移.
- 为了确定与巴西成年人群中HF发展相关的因素.
主要方法:
- 一项队列研究追踪了14854名来自成人健康纵向研究 (ELSA-巴西) 的参与者超过12年.
- 在三次研究访问 (2008-2018) 中确定了事件性HF病例,不包括基线病例.
- 考克斯回归分析用于确定风险因素,计算危险比率 (HR) 和95%置信区间 (95% CI).
主要成果:
- 肺炎的总发病率为每1000人/年1.35,累计发病率达到1.39%.
- 在老年人 (65-74岁),黑人和超重者中观察到更高的发病率.
- 危险因素包括晚年,腹部肥胖,查加斯病,膜心脏病,吸烟,高血压,类风湿性发烧,胸痛和疲劳.
结论:
- 这项研究揭示了巴西心力衰竭 (HF) 发病率的演变模式.
- 确定了可修改的风险因素,强调了有针对性的预防策略的重要性.
- 调查结果支持需要公共政策,重点关注早期HF检测和管理.
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