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Updated: Sep 11, 2025

Gene Digital Circuits Based on CRISPR-Cas Systems and Anti-CRISPR Proteins
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循环四乙酸结合会诱导蛋白质二元体的二分化,以激活与CRISPR相关的PIN核酶

Fang Wang1, Pengpeng Zhao1, Xiaonan Bi1

  • 1CRISPR and Archaea Biology Research Center, State Key Laboratory of Microbial Technology and Microbial Technology Institute, Shandong University, Qingdao 266237, China.

Nucleic acids research
|August 12, 2025
PubMed
概括

研究人员描述了CaPN,这是一种新的CRISPR-Cas效应蛋白. 它感知循环四甲基乙酸 (cA4) 激活RNA裂变,调解古生物的抗病毒防御.

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