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Updated: Sep 11, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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增加的ErbB2信号传递是对抗雄激素信号传递抑制的早期适应,并且在抵抗割的前列腺癌中持续存在

Jude Owiredu1, Betul Ersoy-Fazlioglu2, Larysa Poluben2

  • 1Weill Cornell Medicine, New York, MA, United States.

Clinical cancer research : an official journal of the American Association for Cancer Research
|August 12, 2025
PubMed
概括

由NRG1和d16ERBB2驱动的ErbB2信号的增加,是对抗雄激素信号抑制的快速适应,并促进抵抗割的前列腺癌. ErbB2 抑制剂可能会改善治疗结果.

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