当前的手术治疗策略和局部复发性直肠癌的持续问题
Yasuyuki Yokoyama1, Kay Uehara1, Takeshi Yamada1
1Department of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
Japanese journal of clinical oncology
|August 12, 2025
概括
管理局部复发性直肠癌 (LRRC) 需要R0切除,通常需要复杂的手术. 本综述探讨了先进的外科手术技术,放射治疗和针对患者的具体规划,以改善结果.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 辐射瘤学 辐射瘤学
背景情况:
- 尽管治疗进展,局部复发性直肠癌 (LRRC) 存在重大管理挑战.
- 实现R0切除对于治愈疗法至关重要,但在技术上要求很高,受瘤位置和专业知识的影响.
研究的目的:
- 审查LRRC目前的外科手术策略.
- 突出解剖学分类,多学科合作和个性化规划的重要性.
主要方法:
- 对LRRC的手术策略进行叙述性审查.
- 讨论扩展切除,微创方法和放射治疗选择.
主要成果:
- 扩展切除和最小侵入性方法提供了扩展的指示,但需要专门的专业知识.
- 碳离子辐射疗法对不可切除的LRRCs具有前景,并且正在对切除的病例进行调查.
- 术前化学辐射疗法对以前没有接受过辐射的患者很重要;重新辐射是有争议的.
结论:
- 最佳的LRRC管理需要采用多学科,个性化的方法,平衡瘤结果和生活质量.
- 共同决策对于定制局部复发性直肠癌治疗计划至关重要.
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