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败血症中循环的无细胞DNA景观主要由肝脏清除受损主导

Kiki Cano-Gamez1, Patrick Maclean2, Masato Inoue3

  • 1Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Department of Clinical and Biomedical Sciences, University of Exeter, Exeter, UK.

Cell genomics
|August 12, 2025
PubMed
概括

循环无细胞DNA (cfDNA) 在败血症中显著增加,不是来自细胞死亡,而是肝脏清除受损. 这种cfDNA为严重感染和危急疾病提供了诊断潜力.

关键词:
通过DNA甲基化.没有细胞的DNA DNA.危急的疾病危急的疾病.表观遗传学是指表观遗传学.在表观基因组学上,表观基因组学.碎片组学 碎片组学感染的感染感染.液体活检是液体活检.转基因组学是指转基因组学.这是一种血症.

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