关于心血管疾病环境风险因素的综合审查/专家声明
Thomas Münzel1, Mette Sørensen2,3, Jos Lelieveld4
1Department of Cardiology, University Medical Center Mainz, Johannes Gutenberg University, Langenbeckstrasse 1, Mainz 55131, Germany.
空气和噪音污染等环境因素显著增加了心血管疾病 (CVD) 的风险. 通过政策和临床整合来解决这些暴露对于公共卫生至关重要.
科学领域:
- 环境健康 环境健康
- 心血管医学 心血管医学
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 仍然是全球主要的死亡原因.
- 传统的风险因素是众所周知的,但环境暴露越来越被认为是显著的贡献者.
- 新出现的证据强调了空气污染,噪音,热量,化学品和微/纳米塑料对心血管健康的影响.
研究的目的:
- 审查环境暴露对心血管健康的影响.
- 突出污染影响心血管系统的机制.
- 倡导将暴露组框架纳入风险评估和预防策略.
主要方法:
- 审查最近的翻译和流行病学研究.
- 分析包括氧化应激,炎症和昼夜干扰在内的机制.
- 检查新的威胁,如微型和纳米塑料和气候变化的影响.
主要成果:
- 长期暴露于交通噪音,空气污染 (即使低于法规限制),以及其他环境因素会增加心肌梗塞,中风和心力衰竭的风险.
- 这些暴露会促进动脉样硬化,血管功能障碍和全身炎症.
- 气候变化加剧了心血管疾病的风险,特别是在弱势群体中.
结论:
- 环境决定因素对全球心血管疾病负担作出了重大贡献.
- 目前的预防策略不足以应对累积的环境暴露.
- 系统性干预,政策行动和将环境健康纳入临床实践对于保护心血管健康至关重要.
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