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Updated: Sep 11, 2025

Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae
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基质结构 确定人体细胞中的p97-和RAD23A/B介导蛋白质体降解

Yi Ding1, Takuya Tomita1, Hikaru Tsuchiya2,3

  • 1Division of Protein Metabolism, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

Journal of biochemistry
|August 12, 2025
PubMed
概括

基质结构决定了蛋白质体降解中对p97和RAD23A/B的需求. 非结构化的蛋白质绕过这些因素,帮助有针对性的蛋白质降解策略.

关键词:
在RAD23A/B上使用.在P97中,P97是P97的代码.基板结构的基板结构.乌比奎丁的融合降解降解乌比奎丁-蛋白酶体系统

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