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Updated: Sep 11, 2025

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通过O-GlcNAcylation对KLHL3/WNK通路的功能调节的证据

Jimin Hu1, Duc T Huynh1, Denise E Dunn2

  • 1Department of Biochemistry, Duke University School of Medicine, Box 3711 DUMC, Durham, NC 27710, United States.

Glycobiology
|August 12, 2025
PubMed
概括

与O相关的β-N-乙糖胺 (O-GlcNAc) 修改了包括KLHL3在内的Kelch样 (KLHL) 蛋白,影响WNK激酶功能. 这种糖化调节细胞过程,如度控制和铁,对健康至关重要.

关键词:
在 KLHLHL KLHL这就是O-GLcNAcc.这是WNK的WNK.信号传输,信号传输.

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