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Updated: Sep 11, 2025

Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood
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Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood

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开发了来自Lamprey的抗体来对抗人类血型抗原

Pascal B Kunz1,2, Ea Kristine Clarisse Tulin1, Akul Y Mehta1

  • 1Department of Surgery, Beth Israel Deaconess Medical Center, National Center for Functional Glycomics, Harvard Medical School, Boston, MA.

Glycobiology
|August 12, 2025
PubMed
概括

研究人员利用海的免疫力开发了新的单克隆抗体 (mAbs),以检测红细胞 (RBC) 上的特定碳水化合物抗原. 这些新型试剂向H抗原和N-乙酸氨酸胺 (LacNAc),有助于糖甘研究.

关键词:
在ABO血型抗原.糖甘油的使用方法葡萄糖生物学 葡萄糖生物学鱼的抗体 鱼抗体一个单克隆抗体.

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The ABO Blood Group

The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
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