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Updated: Sep 11, 2025

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TGF-β诱导CAPZA1表达的减少,以促进肝细胞癌细胞的侵入性.

Le Xiao1, Li Cao2, Zhulin Luo3

  • 1Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, PR China; Department of General Surgery, The General Hospital of Western Theater Command, Chengdu, Sichuan Province 610083, PR China.

The American journal of the medical sciences
|August 12, 2025
PubMed
概括

转化生长因子β (TGF-β) 通过降低GATA3来降低CAPZA1表达,从而提高肝细胞癌 (HCC) 细胞的侵入性. 准这种TGF-β/GATA3/CAPZA1通路可以抑制HCC转移.

关键词:
在APZA1中使用APZA1.在 Invadopodia 中,我们发现了侵入性 侵袭性 侵袭性在TGF-β信号传输中.

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