相关实验视频

Updated: Sep 11, 2025

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

插入假针的具体效果及其对随机对照试验中针治疗效果估计的影响: 一项系统调查

Xiao-Chao Luo¹, Jia-Li Liu¹, Ming-Hong Yao¹

¹Institute of Integrated Traditional Chinese and Western Medicine and Chinese Evidence-based Medicine Center, Cochrane China Center and MAGIC China Center, West China Hospital, Sichuan University, Chengdu 610041 Sichuan Province, China; NMPA Key Laboratory for Real-world Data Research and Evaluation in Hainan, Chengdu 610041 Sichuan Province, China; Sichuan Center of Technology Innovation for Real-world Data, Chengdu 610041 Sichuan Province, China.

Journal of integrative medicine

|August 12, 2025

概括

插入假针具有特定的效果 (PIES),影响随机对照试验 (RCT) 中针治疗的评估. 控制PIES变化研究结果的控制,建议在使用插入假作为安慰剂时谨慎使用.

科学领域:

综合医学是一个整体的医学.
临床研究方法论临床研究方法论
针研究针研究

背景情况:

在随机对照试验 (RCT) 中使用插入假针作为安慰剂是有争议的,因为潜在的特定效应.
这些影响可能会导致低估真正的针治疗疗效.

研究的目的:

调查假针 (PIES) 的插入特异效应的大小.
确定PIES是否影响RCT中针治疗效果的估计.

主要方法:

对将针与假针和没有治疗进行比较的RCT的系统调查 (PubMed,Embase,Cochrane).
分析量化自然历史 (PNE) 和情境效应 (PCE).
假针 (PIES) 的插入特异效应的计算及其对结果解释的影响.

主要成果:

假针 (PIES) 的插入特异效应占针总效应的18.90%.
排除PIES在45.45%的纳入RCT和40.91%的外部验证RCT中改变了治疗效应的统计学意义.

结论:

在RCT中,PIES对治疗效果的评估产生了重大影响.
超过40%使用插入假针的RCT可能会得出不同的结论,如果PIES受到控制.
在RCT中使用插入假针作为安慰剂时建议谨慎使用.

关键词:

针是一种针疗法.取代剂是什么意思取代剂是什么意思随机对照试验是随机对照试验.治疗结果的结果.

更多相关视频

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

Monitoring Acupuncture Effects on Human Brain by fMRI

Monitoring Acupuncture Effects on Human Brain by fMRI

Published on: April 8, 2010

相关概念视频

Blinding

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

Blind Procedures

Blind Procedures

Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...