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Updated: Sep 11, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

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一个STUB1-CHIC2复合体抑制CD8+T细胞以抑制瘤免疫力

Martin W LaFleur1,2, Lauren E Milling3,4, Priyamvada Prathima3,4

  • 1Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. martin_lafleur@hms.harvard.edu.

Nature immunology
|August 12, 2025
PubMed
概括

科学家们发现STUB1是抗瘤CD8+T细胞功能的负调节者. 抑制STUB1-CHIC2通路可以增强CD8+T细胞对癌症的免疫力.

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