优化林奇综合征的监测:病变检测和不同结肠镜方式的比较性能-系统性审查和网络元分析
George Hanen1, Hazem E Mohammed2, Mohamed Nasser1
1School of Medicine, Minia University, Minia, Egypt.
与白光内镜相比,链接色彩成像 (LCI) 和染色内镜显著改善了林奇综合征患者的瘤病变检测. 虽然有效,但染色内镜增加了手术时间,人工智能技术需要进一步研究.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 林奇综合征显著增加结直肠癌的风险,需要加强监测.
- 目前的结肠镜成像方法在诊断效率上有所不同,在林奇综合征患者中直接比较有限.
研究的目的:
- 为了比较白光内镜 (WLE),染色内镜,虚拟染色内镜 (NBI,LCI,I-SCAN) 和人工智能辅助结肠镜的病变检测能力.
- 评估这些方法来检测林奇综合征患者的瘤和非瘤病变.
主要方法:
- 在PubMed,WOS和Scopus的系统文献搜索到2025年3月.
- 包括观察性或干预性研究,比较成年林奇综合征患者的结肠镜技术.
- 主要结局:病变检测率和病变数量;次要结局:程序和等待时间. 使用CINeMA工具进行信誉评估.
主要成果:
- 结合色彩成像 (LCI) 和染色内镜显示,瘤病变检测率明显高于WLE.
- 在每次手术中,LCI检测到更多的病变;在非新生病变的病变识别方面,染色内镜更优越,但增加了手术时间.
- 人工智能辅助和虚拟染色内镜方法的性能优于WLE,但效果不如LCI或标准染色内镜.
结论:
- 在林奇综合征监测中,LCI和染色内镜增强了WLE用于检测瘤病变.
- 染色内镜对于非新生病变有价值,尽管手术时间是一个限制.
- 人工智能辅助结肠镜显示出有希望的结果,但需要进一步研究临床应用.
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