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恩多利辛在来自细菌性阴道炎妇女的阴道样本中选择性地杀死Gardnerella ex vivo

Lenka Podpera Tisakova1, Timo Schwebs1, Rocío Berdaguer1

  • 1BioNTech R&D (Austria) GmbH, Vienna, Austria.

NPJ biofilms and microbiomes
|August 12, 2025
PubMed
概括

复发性细菌性阴道炎 (BV) 可以用BNT331-endolysin (BNT331-EL) 治疗,该药物向Gardnerella生物膜. 活体研究表明,BNT331-EL显著减少了加德内拉菌,同时保留了有益的乳酸菌.

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