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Updated: Aug 16, 2026

Isolating Potentiated Hsp104 Variants Using Yeast Proteinopathy Models
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对于过度表达的人类α-synuclein的质突触弹性

Patrícia I Santos1, Inés Hojas García-Plaza2, Ali Shaib3

  • 1Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, Göttingen, Germany.

NPJ Parkinson's disease
|August 12, 2025
PubMed
概括

在动物神经元中过度表达alpha synuclein (aSyn) 并没有损害前突触功能或引起毒性. 这些发现表明,帕金森病 (PD) 中aSyn神经毒性可能不仅仅是由于过度表达.

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