内脏脂肪和牛皮的代谢得分之间的关联:来自NHANESES的发现
Xinyi Shao1, Yi Ou1, Qian Liu1
1Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
European journal of medical research
|August 12, 2025
概括
内脏脂肪的代谢得分 (METS-VF) 与牛皮风险增加有关. 较高的METS-VF水平与患这种炎症性皮肤疾病的可能性更大.
科学领域:
- 皮肤病学 皮肤病学
- 代谢健康 代谢健康
- 流行病学 流行病学
背景情况:
- 牛皮是一种慢性炎症性皮肤疾病.
- 肥胖是一种已知的牛皮发育和进展的风险因素.
- 内脏脂肪的代谢得分 (METS-VF) 是评估内脏肥胖症的新型指标.
研究的目的:
- 调查METS-VF与牛皮发病率之间的关联.
- 利用来自国家健康和营养检查调查 (NHANES) 的数据.
主要方法:
- 来自NHANES (2003-2014) 的全国代表性队列 (n=8023) 的分析.
- 使用多变量逻辑回归和受限立方线 (RCS) 分析.
- 进行了子组分析,以确定敏感人群.
主要成果:
- 在METS-VF和牛皮风险之间发现了显著的积极关联.
- 每增加1个单位的METS-VF对应于47%的牛皮风险增加 (OR=1.47,95%CI=1.10-1.96).
- 这种关联在所有子组中都是一致的,通过RCS分析表明了线性关系.
结论:
- 较高的METS-VF水平与较高的牛皮发病率有关.
- METS-VF可以作为一种有价值的预测性人体指数,用于牛皮风险评估.
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