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抑制Setd7可以通过抑制脂质氧化来保护心肌细胞增大

Hai-Bi Su1, Jing-Huan Wang1, Yu-Yu Zhang1

  • 1Phenome Research Center of TCM, Department of Traditional Chinese Medicine, Shanghai Pudong Hospital, Pharmacophenomics Laboratory, Human Phenome Institute, Fudan University, Shanghai, 200120, China.

Acta pharmacologica Sinica
|August 13, 2025
PubMed
概括

含有SET域的蛋白7 (Setd7) 在缺氧下通过降解谷氨过氧化酶4 (GPx4) 来促进心脏缩. 准Setd7可能为缺氧引起的心力衰竭提供治疗策略.

关键词:
在GPx4中使用.在RSL3中使用RSL3.第七百七十七章 设定心肌细胞的过度增大缺氧 缺氧是指缺氧的情况.脂质过氧化过氧化

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