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Updated: Sep 11, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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野生类型的p53过度表达抑制了DNA损伤途径,并减少了前列腺癌中的PD-L1表达

Heng Zhang1, Guojun Lu2, Yang Hu1

  • 1Department of Urology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.

Journal of immunotherapy (Hagerstown, Md. : 1997)
|August 13, 2025
PubMed
概括

野生型p53 (WT-p53) 通过抑制DNA损伤反应 (DDR) 途径来抑制前列腺癌的进展. 这导致PD-L1和PARP1的表达减少,促进细胞亡和减少瘤细胞的增殖.

关键词:
它们是DNA DNA DNA DNA.对DNA损伤的反应反应在PD-L1中.在p53中,p53是什么?前列腺癌是前列腺癌.

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