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Updated: Jul 9, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
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呈现毒素菌密集颗粒蛋白7的流感病毒样颗粒保护小鼠免受致命的ME49挑战

Jie Mao1,2, Hae-Ji Kang3, Su-In Heo1

  • 1Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea.

Nanomedicine (London, England)
|August 13, 2025
PubMed
概括

一种使用Toxoplasma gondii密集颗粒抗原7 (GRA7) 病毒样颗粒 (VLPs) 的新型疫苗在小鼠中证明了对慢性毒素菌的100%存活率,提供了显著的保护.

关键词:
在 GRA7 中,GRA7 是最常见的.这种毒性淋巴细胞 (Toxoplasma gondii) 是免疫保护 免疫保护 免疫保护疫苗 疫苗 疫苗 疫苗类似病毒的颗粒.

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Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...