胃食道逆流性疾病相关的瘤的内镜下粘膜剖析
Zhukai Chen1, Zhuyun Leng, Jiacheng Xu
1Department of Gastroenterology, School of Medicine, Tongji University, Endoscopy Center, Shanghai East Hospital, Shanghai, China.
Surgical laparoscopy, endoscopy & percutaneous techniques
|August 13, 2025
概括
内镜下粘膜切割 (ESD) 有效地治疗胃食道逆流性疾病 (GERD) 相关的瘤,切除率高,症状缓解的机会很大. 这种程序为管理这些条件提供了安全有效的选择.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 内視鏡外科手術 內視鏡外科手術
背景情况:
- 胃食道逆流性疾病 (GERD) 显著影响生活质量,并与食道癌症有关.
- 内镜下粘膜切割 (ESD) 是一种微创的技术,用于切除胃食道结 (GEJ) 瘤.
- 理论上,ESD通过在切割后重塑胃心脏门来减少GERD.
研究的目的:
- 评估ESD对与GERD相关的瘤的安全性和有效性.
- 评估ESD对GERD症状缓解的影响.
主要方法:
- 对96名患有与GERD相关的瘤的患者进行了回顾性分析,这些患者接受了ESD治疗.
- 收集的数据包括临床,内镜,组织学和随访信息.
- 随访评估了局部复发,转移和GERD症状状态.
主要成果:
- 100%的块切除,99.0%的完整切除和95.8%的治愈切除率.
- 主要并发症率为8.4%;没有观察到局部复发或转移.
- 69.6%的患者在6个月后经历了GERD症状缓解,受切除的光圈周长的影响.
结论:
- 对于与GERD相关的瘤来说,ESD是一种安全有效的治疗方法.
- 在很大一部分患者中,ESD在缓解GERD症状方面表现出有效性.
- 切除的光圈周长是ESD后GERD症状改善的关键因素.
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