在Soweto的复杂心理药物多药房社区精神病诊所
Lee-Ann Mabulwana1, Kagisho Maaroganye1
1Department of Psychiatry, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
概括
复杂的精神药物多药 (CPP) 影响了南非25.3%的患者. 寡妇或离婚的人面临更高的CPP风险,需要仔细审查药物.
科学领域:
- 精神病学是一个精神病学.
- 临床药房 临床药房
- 公共卫生 公共卫生
背景情况:
- 复杂的精神药物多药 (CPP) 是一个日益增长的全球关注.
- 在南非,CPP的患病率很高,与不良药物反应和较差的患者结果有关.
- 在南非背景下,关于CPP风险因素的数据有限.
研究的目的:
- 确定南非社区心理健康环境中CPP的流行情况.
- 在这个人群中确定与CPP相关的临床和社会人口统计因素.
主要方法:
- 一项回顾性研究分析了来自索韦托的五家社区心理健康诊所的348名成年患者记录.
- 数据包括处方,临床和社会人口统计学变量;CPP被定义为3+精神药物.
- 统计分析包括基平方测试和后勤回归来确定CPP风险因素.
主要成果:
- 发现CPP的患病率为25.3%.
- 精神病诊断 (p=0.012) 和丧偶或离婚 (AOR=4.3) 与CPP有显著的相关性.
- 抗胆固醇药物的使用是最常见的不良反应 (13.2%),其中28.3%的患者在CPP.
结论:
- 该研究强调了南非CPP的大量流行.
- 增加的药物负担与更高的副作用风险相关.
- 强调基于证据的处方和定期的药物审查对于管理CPP至关重要.
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