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Updated: Sep 11, 2025

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry
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Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

Published on: May 17, 2016

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通过促进通过差异化和CYLD的生存,MyoD在狂宫肌肉瘤中至关重要

Alexander R Oles1, Peter Y Yu2, Abasi-Ama Udeme1

  • 1Department of Pediatrics, Darby Children's Research Institute, Medical University of South Carolina, Charleston, SC 29425, USA.

iScience
|August 13, 2025
PubMed
概括

令人惊的是,拉布多米索尔科马瘤细胞通过由MyoD控制的部分分化而生存,而不是NF-κB. 丢失MyoD使这些癌细胞敏感到死亡,这表明MyoD在这种儿科癌症中充当瘤基因.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学

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