大动脉置换中的萨尔科佩尼亚的预后值:系统性审查和元分析
Jie He1,2
1School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan, China.
Frontiers in nutrition
|August 13, 2025
概括
肌肉损失的疾病 - - 萨科佩尼亚 - - 在接受主动脉置换 (SAVR或TAVR) 的患者中很常见. 这种肌肉消耗状况在这些心脏手术后显著增加了长期死亡风险.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 外科手术的结果
背景情况:
- 萨科佩尼亚是心血管疾病中越来越令人担忧的一个问题.
- 大动脉置换,手术 (SAVR) 和透导管 (TAVR) 都是大动脉疾病的常见程序.
- 了解萨科佩尼亚对这些干预措施后的结果的影响至关重要.
研究的目的:
- 在接受SAVR和TAVR的患者中量化类病的患病率.
- 评估萨科佩尼亚和SAVR和TAVR后死亡风险之间的关联.
主要方法:
- 从主要数据库 (PubMed,Embase,Web of Science等) 进行研究的系统审查和元分析. 在2025年7月之前.
- 患病率和死亡风险 (HR/OR与95% CI) 通过使用Stata 11.0.0中的统计分析来计算.
- 使用I2统计学来评估异质性.
主要成果:
- 包括38项研究,其中6项是SAVR,32项是TAVR.
- 在SAVR患者中,肉类的患病率为31.3%,在TAVR患者中为43.7%.
- 在SAVR (HR=3.10) 和TAVR (HR=1.25) 队列中,皮症与长期死亡率显著增加有关.
结论:
- 在接受SAVR和TAVR两种治疗的患者中,肉症的患病率很高.
- 萨科佩尼亚是大动脉置换手术后长期死亡率增加的重要预测因素.
- 这些发现强调了在接受主动脉干预的患者的管理中考虑肉类症的重要性.
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