关于肠道微生物群和胆汁酸之间的相互作用的全球研究趋势:一个图书统计和可视化分析
Fangli Luo1,2,3, Luqiang Sun3, Renhong Wan3
1Department of Traditional Chinese Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Frontiers in cellular and infection microbiology
|August 13, 2025
概括
这项研究分析了20年来肠道微生物和胆酸相互作用,揭示了关键研究趋势. 主要主题包括代谢疾病,癌症和炎症,突出显示未来的研究方向.
科学领域:
- 微生物组研究 微生物组研究
- 代谢生物化学 代谢生物化学
- 免疫学 免疫学 免疫学
背景情况:
- 肠道微生物群和胆酸相互作用对宿主健康和疾病至关重要.
- 了解这些相互作用对于开发新的治疗策略至关重要.
研究的目的:
- 在过去二十年 (2004-2024) 中对肠道微生物群与胆酸相互作用的全球科学成果进行文献分析.
- 确定研究热点,有影响力的出版物和该领域的新兴前沿.
主要方法:
- 从科学网络核心集合 (2004-2024) 中对4795篇文章和评论进行了图书统计分析.
- 使用包括VOSviewer,Tableau,Scimago Graphica和CiteSpace在内的工具进行数据分析.
- 分析出版物,国家,机构,期刊,作者,参考文献和关键词.
主要成果:
- 随着时间的推移,出版物数量迅速增加,中国在产量方面领先,美国在引用方面领先.
- 上海嘉通大学和贾伟分别是最有成效的机构和作者.
- 炎症,代谢性疾病 (肥胖,2型糖尿病) 和癌症 (结肠直肠癌) 成为关键研究领域.
结论:
- 图书计量分析提供了关于肠道微生物组-胆酸研究不断变化的景观的见解.
- 确定了当前的热点和未来的研究方向,包括Tgr5和途径参与.
- 为未来在这个充满活力的科学领域的研究提供指导.
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