感知压力和MAFLD之间的关联部分介于吸烟和饮酒
Yan Gong1, Shengshu Wang2, Jianan Jiang3
1Department of Health Medicine, Second Medical Center and National Clinical Research Center for Geriatric Disease, Chinese PLA General Hospital, Beijing, China.
Frontiers in medicine
|August 13, 2025
概括
高感知压力与代谢功能障碍相关的脂肪肝疾病 (MAFLD) 的风险增加有关. 吸烟和饮酒部分调解了这种关联,强调了有针对性的公共卫生干预措施的需要.
科学领域:
- 代谢健康 代谢健康
- 胃肠病学 胃肠病学
- 精神病体医学是一种精神病体医学.
背景情况:
- 压力与非酒精性脂肪性肝病 (NAFLD) 之间的联系被建议,但感知压力对代谢功能障碍相关的脂肪性肝病 (MAFLD) 的影响仍然未被探索.
- 这项研究调查了感知压力和MAFLD之间的关联.
研究的目的:
- 检查感知压力水平与MAFLD患病率之间的关系.
- 为了确定潜在的调解因素,如吸烟和饮酒,在感知压力和MAFLD之间的关联.
主要方法:
- 这是一项对2011年至2021年期间接受健康检查的36847人进行的横截面研究.
- MAFLD诊断标准包括脂肪肝和代谢功能障碍;感知压力被评估使用感知压力量表 (PSS-14).
- 使用后勤回归和调解分析来探索吸烟和饮酒的关联和调解作用.
主要成果:
- MAFLD的患病率为37.10%,其中MAFLD的患病率为37.10%.
- 较高的感知压力水平与较高的MAFLD发病率 (40.4%对34.9%,P<0.001) 有显著的关联.
- 感知压力与MAFLD (OR 1.076,P = 0.036) 有积极的关联,吸烟和饮酒部分介导,观察到协同效应.
结论:
- 这项研究提供了证据表明,感知压力与MAFLD之间存在积极的关联.
- 吸烟和饮酒被确定为感知压力和MAFLD之间的关系的部分调解者.
- 公共卫生倡议应解决吸烟和饮酒问题,特别是在高压力的人群中,以减轻MAFLD风险.
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