相关实验视频

Updated: Jul 23, 2026

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

15.8K

将亨廷顿病研究与大数据科学相结合:来自多项研究的协调的神经成像数据集

Dorian Pustina1, Sandhitsu Das2, Dan Rozelle3

  • 1CHDI Management, Inc. (the company that manages the scientific activities of CHDI Foundation, Inc.), Princeton, NJ, United States.

Imaging neuroscience (Cambridge, Mass.)
|August 13, 2025
PubMed
概括

这项研究为协调亨廷顿病 (HD) 神经成像数据提供了一个新的平台,使其可供研究使用. 该平台将数据格式标准化,并将多项研究的信息结合起来,以方便分析.

关键词:
在这里,PET是PET.临床临床临床临床临床临床临床联邦联合会 联邦联合会这是FMRI.建模 建模模型 建模模型这是一种治疗疗法.

更多相关视频

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease09:06

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease

Published on: June 9, 2018

12.2K
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.4K

相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Huntington Disease l: Introduction01:21

Huntington Disease l: Introduction

Huntington disease or HD is a progressive, fatal neurodegenerative disorder inherited in an autosomal dominant pattern.PathophysiologyIt is caused by expansion of the CAG trinucleotide repeat in the HTT gene on chromosome 4 (4p16.3), producing an abnormal huntingtin protein with an expanded polyglutamine tract. This misfolded protein disrupts cellular function, leading to neuronal death. Normal alleles have ≤26 repeats, 27–35 are intermediate (risk of expansion), 36–39 show reduced penetrance,...