对核的结构预测与人类风险偏好的冲动成分有关
Loreen Tisdall1, Kelly MacNiven2, Josiah Leong3
1Center for Cognitive and Decision Sciences, University of Basel, Basel, Switzerland.
Imaging neuroscience (Cambridge, Mass.)
|August 13, 2025
概括
大脑与脑核 (NAcc) 的连接影响了风险承担. 特定的途径将冲动性与NAcc联系起来,而一般的风险偏好可能涉及前额-三角形连接,为决策提供了洞察力.
科学领域:
- 神经科学是一个神经科学.
- 行为经济学是一种行为经济学.
- 心理测量 心理测量 心理测量
背景情况:
- 核子中对线索的功能反应 (NAcc) 预测了现实生活中的冒险行为.
- NAcc活动依赖于来自连接的大脑区域的神经传递,这表明预测也可能预测风险偏好.
研究的目的:
- 调查风险偏好心理测量因素与NAcc.投影的白质微观结构 (微分异性) 之间的关联.
- 测试有关特定大脑区域到NAcc通路的假设及其与一般风险偏好和冲动性的关系.
主要方法:
- 利用了先前研究风险偏好结构的潜在变量,包括一般风险偏好因子和冲动性因子.
- 采用扩散张力成像来测量连接中介前额叶皮层 (MPFC),前侧胰岛,杏仁体和下腹垂体区域 (iVTA) 到NAcc.cc的通道中的分数异构 (FA).
- 在125名健康成年人的社区样本中测试了假设.
主要成果:
- 双边IVTA-NAcc通道FA与冲动性负相关,支持先前的研究.
- 双边桃体-NAcc通道FA与冲动性积极相关.
- 对于MPFC,前胰岛或杏仁体对NAcc的预测,没有发现一般风险偏好因素和FA之间的强有力的关联;然而,探索性分析显示左MPFC-NAccFA和一般风险偏好之间存在联系.
结论:
- 冲动控制,风险偏好的一个方面,与特定的神经生物学目标有关 (iVTA和杏仁体对NAcc的预测).
- 一般风险偏好可能得到侧面前-角突出的结构性质 (例如,左MPFC-NAcc通道) 的支持.
- 连接的方法为了解风险偏好的生理基础提供了潜力.
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